// Compound catalog

Compound catalog

22 therapeutic peptides — mechanism, pharmacokinetics, dosing, safety, evidence grade, and cross-links to the modules that teach them.

22 of 22 shown
GLP-1 receptor agonist

Semaglutide

aka Ozempic · Wegovy · Rybelsus
Grade A

Weekly GLP-1 RA — pivotal A-grade evidence in T2D, obesity, and CVD risk reduction.

FDA-approved
Dual GIP / GLP-1 receptor agonist

Tirzepatide

aka Mounjaro · Zepbound
Grade A

First dual incretin agonist — ~20% mean weight loss at 15 mg in obesity.

FDA-approved
GLP-1 receptor agonist (daily)

Liraglutide

aka Victoza · Saxenda
Grade A

Daily lipidated GLP-1 RA — first agent with CV outcome benefit (LEADER, 2016).

FDA-approved
GIP / GLP-1 / Glucagon triple agonist

Retatrutide

Grade B

Triagonist showing ~24% weight loss at 48 weeks in phase 2 — phase 3 ongoing.

Investigational
GHRH analog

Tesamorelin

aka Egrifta
Grade A

Only FDA-approved GHRH analog — HIV-associated lipodystrophy.

FDA-approved
GHRH(1–29) analog

Sermorelin

Grade C

Truncated GHRH — historically FDA-approved (Geref, withdrawn 2008); now compounded.

Compounded (503A/503B)
Selective GH secretagogue (GHS-R agonist)

Ipamorelin

Grade D

Selective ghrelin-receptor agonist with minimal cortisol/prolactin effect — no human efficacy RCTs.

Compounded (503A/503B)FDA Cat 2
Long-acting GHRH analog

CJC-1295 (with/without DAC)

Grade D

DAC variant binds albumin → multi-day half-life. Not FDA-approved; widely sold grey-market.

Research-only / unregulatedFDA Cat 2
Synthetic pentadecapeptide (gastric origin)

BPC-157

aka Body Protective Compound 157
Grade D

Strong rodent healing data, essentially zero controlled human trials. FDA Cat 2 (2023).

Research-only / unregulatedFDA Cat 2
Synthetic Tβ4 active fragment

TB-500 (Thymosin β4 fragment)

Grade D

Veterinary use exists; no FDA-approved human indication. Often co-marketed with BPC-157.

Research-only / unregulatedFDA Cat 2
Copper tripeptide-1 (Gly-His-Lys + Cu²⁺)

GHK-Cu

Grade C

Modest A-grade evidence as a topical cosmeceutical; systemic 'anti-aging' claims are unsupported.

Compounded (503A/503B)
Mitochondrial-derived peptide (MDP)

MOTS-c

Grade D

Encoded by mitochondrial 12S rRNA — exciting biology, no human therapeutic data.

Investigational
Melanocortin receptor agonist (MC1R/MC3R/MC4R)

PT-141 (Bremelanotide)

aka Vyleesi
Grade B

FDA-approved for HSDD in premenopausal women; widely misused off-label for ED.

FDA-approved
Non-selective melanocortin receptor agonist

Melanotan II

Grade F

Banned in multiple countries; serious AEs including melanoma transformation reports.

Research-only / unregulated
Posterior pituitary nonapeptide

Oxytocin

aka Pitocin
Grade A

Foundational obstetric peptide — induction, augmentation, postpartum hemorrhage.

FDA-approved
Synthetic vasopressin V2-selective analog

Desmopressin (DDAVP)

Grade A

V2-selective ADH analog — central DI, nocturnal enuresis, mild hemophilia A / vWD.

FDA-approved
GnRH receptor superagonist

Leuprolide

aka Lupron
Grade A

Chemical castration via continuous GnRH agonism — prostate cancer, endometriosis, central precocious puberty, GAHT.

FDA-approved
Somatostatin analog

Octreotide

aka Sandostatin
Grade A

Workhorse somatostatin analog — acromegaly, NETs, variceal bleeding, refractory diarrhea.

FDA-approved
Synthetic tuftsin analog (anxiolytic peptide)

Selank

Grade D

Russian-origin nootropic — small non-blinded studies; not FDA-approved.

Research-only / unregulated
Synthetic ACTH(4–10) analog

Semax

Grade D

Sister Russian nootropic to Selank — same evidence caveats.

Research-only / unregulated
Khavinson 'bioregulator' tetrapeptide (Ala-Glu-Asp-Gly)

Epitalon (Epithalon)

Grade F

Decades of Russian institutional research from a single group; no FDA approval, no independent RCTs.

Research-only / unregulatedFDA Cat 2
Khavinson tripeptide (Glu-Asp-Arg)

Pinealon

Grade F

Even thinner literature than Epitalon — almost entirely cell-culture and rodent from one group.

Research-only / unregulatedFDA Cat 2