Visual reference

Media Library

Every interactive diagram, figure, and downloadable cheatsheet from the course — searchable and indexed to module IDs. Use these as visual aids when teaching, counseling, or chart-noting.

14 of 14 items
Diagram

Peptide drug class map

Therapeutic peptide classesPeptide drugs2–50 amino acidsReplacementinsulin · GH · ADHReceptor agonistsGLP-1 RAs · oxytocinAntagonists / suppressionleuprolide · octreotideInvestigational / greyBPC-157 · MOTS-c · GHK-Cu

How therapeutic peptides span replacement hormones, receptor agonists/antagonists, and investigational compounds.

Diagram

Evidence pyramid for peptide claims

Evidence tiersTier 1Pivotal RCT · FDA label · guidelineTier 2Peer-reviewed clinical trials · meta-analysesTier 3Mechanistic · preclinical · case · vendor claim

Three-tier system used throughout the course: pivotal/regulatory, peer-reviewed clinical, mechanistic/preclinical.

Figure

Peptide half-life engineering

Half-life engineering (log scale)Native GLP-1~2 minExenatide~3 hLiraglutide~13 hSemaglutide~7 dTirzepatide~5 d

Native GLP-1 (~2 min) → liraglutide (~13 h) → semaglutide (~7 d): how acylation and modifications extend duration of action.

Diagram

The incretin axis

Incretin axisL-cells (ileum)GLP-1K-cells (jejunum)GIPβ-cell↑ insulin (glucose-dep)α-cell↓ glucagonStomach↓ emptyingHypothalamus↑ satietyCardiac / renalSELECT · FLOW

GLP-1 and GIP release after a meal — pancreatic β-cell, α-cell, gastric, and CNS targets.

Diagram

GLP-1 receptor agonist mechanism

GLP-1 RA mechanismGLP-1 receptor agonistsemaglutide · liraglutide · dulaglutideGlucose-dep insulin↑ at high BG onlyGlucagon↓ postprandialGastric emptying↓ early satietyCentral satietyARC POMC ↑Cardiac/renalMACE / eGFR

Glucose-dependent insulin release, glucagon suppression, gastric emptying, and central satiety pathways.

Diagram

GH secretagogue axis

GH secretagogue axisHypothalamusGHRH · somatostatinAnterior pituitaryGH pulseLiver · IGF-1CJC-1295GHRH analogIpamorelinghrelin mimetic (GHSR)

GHRH analogs (CJC-1295) vs ghrelin mimetics (ipamorelin): pulsatile vs sustained GH release.

Diagram

BPC-157 proposed mechanisms

BPC-157 — proposed mechanismsBPC-157 (pentadecapeptide)mostly preclinical · single-lab dominanceAngiogenesisVEGFR-2 ↑NO pathwayeNOS modulationGrowth-factor X-talkFAK · paxillin

Angiogenesis, NO pathway modulation, growth-factor receptor crosstalk — predominantly preclinical.

Diagram

Melanocortin receptor map

Melanocortin receptorsMC1RSkin pigmentafamelanotideMC2RAdrenal cortexACTHMC3REnergy / inflamresearchMC4RAppetite · sexsetmelanotide · bremelanotideMC5RExocrine glandresearch

MC1R–MC5R targets: pigmentation, energy balance, sexual function, exocrine — and where bremelanotide and setmelanotide bind.

Diagram

HPG axis & GnRH analogs

HPG axis · GnRH analogsHypothalamuspulsatile GnRHPituitaryLH · FSHGonadT · E2Leuprolidecontinuous → flare → ↓Degarelix / relugolixantagonist · no flare

Pulsatile vs continuous GnRH stimulation, agonist flare, and antagonist suppression.

Diagram

503A / 503B / unregulated tiers

US regulatory tiersFDA-approvedNDA/BLA · semaglutide · tirzepatide · setmelanotide503B outsourcing facilityregistered · cGMP-like · larger batches503A patient-specific compoundingstate-licensed · per-patient Rx · category limitsUnregulated 'research peptide'no GMP · no testing · not legal for human use

Regulatory landscape for compounded peptides in the United States.

Downloadable cheatsheet

GLP-1 counseling pocket card

Printable cheatsheet — click download

Initiation, titration, MTC/pancreatitis screen, GI side-effect coaching.

Downloadable cheatsheet

Compounded peptide decision tree

Printable cheatsheet — click download

When 503A is appropriate, when it isn't, and the 2023 Category 2 list.

Downloadable cheatsheet

Full course summary (all 15 modules)

Printable cheatsheet — click download

PDF export of every module's takeaways, claims, and key references.